mast cell — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP1497L	Mast Cell Degranulating Peptide HR-2 acetate	Mast Cell Degranulating Peptide HR-2 acetate(80388-04-1 free base)	Others
	Mast Cell Degranulating Peptide HR-2 acetate from giant hornet Vespa orientalis that has biological effects similar to mast cell degranulating peptide from bee venom.		Others
TP1568	Mast cell degranulating peptide (28-49)
	Mast cell degranulating peptide (28-49) is a bee venom depolarizer that can improve the cGMP content of cerebellum tablets in mice.
TP1497	Mast Cell Degranulating Peptide HR-2
	Peptide from giant hornet Vespa orientalis that has biological effects similar to mast cell degranulating peptide from bee venom.
T9689	M4205		c-Kit
	M4205 is an inhibitor of c-Kit exhibiting high activity on c-Kit mutations in exons 11, 13, 17.		c-Kit
T6488	Epinastine hydrochloride	Alesion,Epinastine HCl,WAL-801CL HCl,Elestat	5-HT Receptor , Histamine Receptor
	Epinastine hydrochloride (WAL-801CL HCl) is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.		5-HT Receptor , Histamine Receptor
T0994	Ketotifen fumarate	HC 20511 fumarate	PDE , Histamine Receptor
	Ketotifen fumarate (HC 20511 fumarate) is a cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators.		PDE , Histamine Receptor
T15259	Evatanepag	CP-533536 free acid	Prostaglandin Receptor
	Evatanepag (CP-533536 free acid) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.CP-533536 demonstrated the ability to heal fractures when administered l...		Prostaglandin Receptor
T0211	Azelastine	Azelastina,Astelin,Azelastinum	SARS-CoV , Histamine Receptor
	Azelastine (Azelastinum) is a phthalazine derivative, and is an histamine antagonist and mast cell stabilizer.		SARS-CoV , Histamine Receptor
T15772	Lodoxamide tromethamine	U-42585E	Histamine Receptor
	Lodoxamide tromethamine is a mast cell stabilizer with anti-allergic properties and can be used in studies about the treatment of asthma and allergic conjunctivitis.		Histamine Receptor
T10811	Chymase-IN-1		Others
	Chymase-IN-1 is a selective, orally active inhibitor of human mast cell chymase (IC50: 29 nM).		Others
T1170	Olopatadine hydrochloride	Olopatadine HCl,KW4679,ALO4943A	5-HT Receptor , Histamine Receptor
	Olopatadine hydrochloride (ALO4943A) is an antihistamine with mast-cell stabilizing properties used as eye drops in the treatment of ALLERGIC CONJUNCTIVITIS.		5-HT Receptor , Histamine Receptor
T4566	Lodoxamide	Lodoxamidum	GPR , Histamine Receptor
	Lodoxamide (Lodoxamidum) is an antiallergic drug acting as a mast-cell stabilizer. It is effective in the treatment of asthma and allergic conjunctivitis.		GPR , Histamine Receptor
T13623	Compound 48/80 trihydrochloride	C48/80 trihydrochloride	Phospholipase
	Compound 48/80 trihydrochloride (C48/80 trihydrochloride) is a mixture of N-methyl-p-methoxyphenethylamine and formaldehyde in a condensation reaction.Compound 48/80 trihydrochloride is a mast cell degranulator and hista...		Phospholipase
T4946	(+)-Columbianetin acetate	COLUMBIANETIN ACETATE	Others
	(+)-Columbianetin acetate (COLUMBIANETIN ACETATE) may be helpful in regulating mast cell-mediated allergic inflammatory responses.The absorption of (+)-Columbianetin acetate is a passive diffusion process without pH-depe...		Others
T29221	(R)-ZINC-3573	ZINC 3573	Others
	(R)-ZINC-3573 is a potent and highly selective MRGPRX2 probe. (R)-ZINC-3573 activates endogenous MRGPRX2 in a human mast cell line, inducing degranulation and calcium release.		Others
TN1516	Cnidicin		NOS , NO Synthase
	Cnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 microM). Cnidicin exhibits a significant inhibition on the pr...		NOS , NO Synthase
T6943	Picropodophyllin	AXL1717,Picropodophyllin (PPP),Picropodophyllotoxin,PPP	Apoptosis , IGF-1R
	Picropodophyllin (Picropodophyllin (PPP)) (PPP) is a specific IGF-1R inhibitor (IC50: 1 nM). Picropodophyllin specifically inhibits the activity and downregulates the cellular expression of IGF1R without interfering with...		Apoptosis , IGF-1R
T25360	Eclazolast	RHC2871,RHC-2871,REV2871,REV 2871,RHC 2871	Others
	Eclazolast (RHC 2871) is a lipophilic anti-allergic compound that inhibits mediator release in a mast cell model.Eclazolast inhibits extracellular secretion by affecting only the direct processes associated with Fc(epsil...		Others
T5S1286	(+)-Columbianetin	(S)-Columbianetin,Columbianetin	Antifungal
	(+)-Columbianetin ((S)-Columbianetin) is a new phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage, it also has antifungal activity. (+)-Columbianetin has anti-inflammatory effect...		Antifungal
T3979	Emedastine	LY188695,Emadine	Histamine Receptor
	Emedastine (LY188695) is a second generation, selective histamine H1 receptor antagonist with anti-allergic activity. Emedastine reversibly and competitively blocks histamine by binding to H1 receptors, thus blocking its...		Histamine Receptor